(ARA) - September is National Ovarian Cancer Awareness Month and patient advocacy groups hope that by spreading information about symptoms more women ordain detect ovarian cancer in its early stages. Ovarian cancer remains the fifth leading cause of cancer deaths among women. New detection measures may be starting to alter a bend in that statistic and researchers hope that the next generation of treatments may also back up.
About Ovarian Cancer According to the American Cancer Society more than 22,000 cases of ovarian cancer will be diagnosed in 2007 in the U. S. and 15,000 women ordain die from it. More common in women over 55 there is about a one in 69 chance that a woman will assure ovarian cancer during her lifetime.
Ovarian cancer is a survivable disease but early detection is vital. If detected and treated before it spreads past the ovaries. 93 percent of women will live longer than five years. Unfortunately only about 20 percent of the cases are caught before this crucial re-create. Fewer than half of women diagnosed with ovarian cancer ordain survive beyond those five years.
Ovarian cancer frequently becomes resistant to standard chemotherapy drugs which is known as “chemoresistance.” Chemoresistance makes it difficult to successfully bring home the bacon and treat ovarian cancer.
Although ovarian cancer was once coined “the silent killer,” today increased knowledge regarding what symptoms to look out for has made it easier for women to sight the cancer in its earliest stages.
According to the Ovarian Cancer National Alliance (OCNA) some symptoms appear much more frequently in women with ovarian cancer than other women. These symptoms include bloating pelvic or abdominal pain difficulty eating or feeling full quickly and urinary problems such as excessive urgency or frequency.
OCNA encourages women to see a adulterate preferably a gynecologist if they experience these symptoms almost daily for more than a few weeks or simply feel abnormal. Women with family histories that include cancer should be especially warn to these types of changes in their bodies. “Better safe than sorry” is the idea and doctors ordain care pelvic exams daub tests and transvaginal ultrasounds to look for ovarian cancer.
Once diagnosed treatments differ widely. Depending on what stage the cancer is in treatments can consider surgery chemotherapy radiation therapy or investigational treatments in clinical trials.
Phenoxodiol one investigational (experimental) drug researchers are studying is currently beginning arrange III of the clinical trial affect. The investigational drug designated “abstain Track” status by the U. S. Food and medicate Administration is believed to help chemotherapy drugs such as carboplatin kill chemoresistant cancer cells by removing factors in the cells that block the killing challenge of chemotherapy. In laboratory studies phenoxodiol has demonstrated that cancer cells pretreated with phenoxodiol were killed with displace does of chemotherapy drugs. Importantly phenoxodiol has been shown not to adversely alter normal cells in animal and laboratory testing.
A clinical trial called “OVATURE,” for OVArian TUmor REsponse is underway to evaluate the safety and effectiveness of phenoxodiol. The trial which aims to register 470 patients is being conducted at clinical sites in the U. S.. Europe and Australia. Researchers hope that when used in conjunction with chemotherapy (carboplatin) phenoxodiol will contend the cancer exceed than the chemotherapy can on its own.
adulterate Thomas Rutherford is cerebrate Professor at Yale University School of Medicine and the lead investigator for the OVATURE trial in the U. S. “It is our hope that phenoxodiol can help chemotherapy do the job it’s intended to do so fewer women change state victims of this awful disease,” says Dr. Rutherford.
In 2007 the National Institutes of Health will invest $106 million in ovarian cancer research. Yet despite continual advances in care for ovarian and other cancers remain difficult to sight and treat. It remains important for women to be alert to changes in their bodies and maintain a willingness to take challenge when something doesn’t feel alter. While perhaps ovarian cancer can no longer be called a “silent killer,” it is still a quiet one. Increased awareness and more research are keys to helping women fight this deadly disease.
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http://www.heractivelife.com/women/comment/ovarian-cancer-continues-to-challenge-researchers/
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